Principle 03

Mechanistic, Not Black-Box

We build models that can explain the biological “why,” not just pattern-match a “what.” Where a decision must be trusted — a variant’s clinical classification, a therapeutic hypothesis — deterministic, source-cited logic leads, and AI augments rather than overrides it.

Every claim should trace back to evidence a human can audit. Interpretability and provenance are features we design for, not compromises we accept.